British researchers were testing a drug intended for use in controlling pulmonary arterial hypertension (PAH) and were somewhat surprised when the male participants reported improved sexual performance. Yet, when they came to analyze the results, the scientists realized the effect they were intending for the major artery through the chest was actually occurring in the penis. (more…)

How Propecia was developed

Humble beginnings

Propecia first hit the market as a drug intended for treatment of enlarged prostate glands in men, back in 1992. It was invented as a result of observations based on sexual development observed in children as they matured. In some boys, a significantly smaller prostate and absence of male pattern baldness was found upon reaching adulthood. Under further examination, hormonal compounds were then discovered that, when isolated, helped with prostate enlargement. It was later noted that patients undergoing treatment also showed improvement in their hair loss. These observations eventually led to the development of the first-ever successful treatment for male pattern baldness. (more…)

Heartburn is one of those sensations that can spoil the aftermath of the tastiest meal you’ve had. We certainly enjoy eating food and the burning sensation in the chest we get with heartburn is a huge pleasure spoiler that can make you think twice before eating anything. Heartburn is usually cause by high acid content in the stomach and structural peculiarities of the gastrointestinal tract that let the half-digested food flow back into the esophagus and damage it. (more…)

Humans just cannot avoid a number of things in their life and the firt sof such things is process of aging. The wise way is to take things as they are. Aging is an unpleasant thing to deal with because of many unwanted processes going on in the body as the person ages. We become weaker, the muscles lose shape, the heart is not as strong as than at youth, the mind isn’t as sharp. Serious hormonal changes occur, the amount of testosterone will drop gradually and the same with libido, family members notice changes in an old persons’ behavior and there are visual changes to our body too. The hormonal changes are believed to be the main reason of hair turning gray and balding – one of the most evident and surely unpleasant signs of aging . (more…)

Long-term use of certain corticosteroids in high doses may cause eye damage. Glaucoma and cataracts are both serious concerns, but how concerned should you be? Should you avoid corticosteroids altogether? Find out the risks below to determine whether it would be wiser to use drugs and monitor the situation closely, as doctors say, or to seek other treatment.

Glaucoma Risks

Glaucoma is a disease characterized by increases of pressure within the eye. There is usually no pain, though pressure is uncomfortable sometimes. It can cause blindness.

As fluid pressure increases, the optic nerve can become damaged. This nerve is essential to working vision. It is hard to detect glaucoma before damage begins, so everyone should get regular eye examinations.

There are many types of glaucoma:

• Secondary glaucoma – occurs as a complication of other conditions and/or medications
• Open-angle glaucoma – fluid builds up because the flow through the eye drain is too slow
• Angle-closure glaucoma – fluid builds up suddenly because of a blockage, causing immediate increase in pressure as well as horrible pain, nausea, vision disruption, and eye irritation; blindness may occur in just days

Secondary glaucoma is the one that corticosteroid users get. Otherwise, glaucoma can occur in anyone, though it is most common in African Americans over 40, Hispanics over 60, people with heart or eye diseases, and those with a history of glaucoma in their families.

How likely are you to get glaucoma if you are on corticosteroids?

Not very likely. It only happens to a small percentage of people. Using it in high levels for many years makes it more likely, but not probable. However, if you also have irritable bowel syndrome, it may be risky to take corticosteroids for very long.

Doctors typically recommend that anyone with severe autoimmune disorders take corticosteroids and have their eye checked regularly for pressure to prevent an issue before the nerve is damaged.

Glaucoma is a permanent condition and will not go away just from ceasing corticosteroid use.

Cataracts Risks

Corticosteroid use over a long period of time may cause certain parts of the body to age earlier. With the eyes, this may result in cataracts.

Most people, should they live to old age, will develop at least one cataract. They develop when proteins clump together in the lens, which makes them opaque (unable to be seen through). (more…)